Päivitetty 07.09.2016

Vakkila J, Lehtonen E, Koskimies S, et al: Dendritic cells in human peripheral blood: effective enrichment from the nonadherent cells. Immunol Lett 15:229-36, 1987

Vakkila J, Myllyla G: Amount and type of leukocytes in ’leukocyte-free’ red cell and platelet concentrates. Vox Sang 53:76-82, 1987

Hurme M, Jalkanen S, Vakkila J: [Leukocyte adhesion molecules and their clinical significance]. Duodecim 104:1507-14, 1988

Silvennoinen O, Vakkila J, Hurme M: Accessory cells, dendritic cells, or monocytes, are required for the lymphokine-activated killer cell induction from resting T cell but not from natural killer cell precursors. J Immunol 141:1404-9, 1988

Vakkila J: Both virgin and memory T cells cluster with dendritic cells during autologous and allogeneic mixed leukocyte reaction. Eur J Immunol 19:1003-8, 1989

Vakkila J, Hurme M: Both dendritic cells and monocytes induce autologous and allogeneic T cells receptive to interleukin 2. Scand J Immunol 31:75-83, 1990

Vakkila J, Sihvola M, Hurme M: Human peripheral blood-derived dendritic cells do not produce interleukin 1 alpha, interleukin 1 beta, or interleukin 6. Scand J Immunol 31:345-52, 1990

Vakkila J, Pihkala U: [Cancer immunotherapy]. Duodecim 115:785-94, 1999

Vakkila J: Syöpä ja immuunijärjestelmä. Säteitä 2:4-7, 2000

Vakkila J, Aysto S, Saarinen-Pihkala UM, et al: Naive CD4+ T cells can be sensitized with IL-7. Scand J Immunol 54:501-5, 2001

Vakkila J, Vettenranta K, Sariola H, et al: Poor yield of dendritic cell precursors from untreated pediatric cancer. J Hematother Stem Cell Res 10:787-93, 2001

Hanninen A, Vakkila J: [Dendritic cell–the conductor of the orchestra of immunological responses]. Duodecim 119:763-72, 2003

Vakkila J, Lotze MT: Cellular Therapy of Cancer. Blood Therapies in Medicine 3:84-90, 2003

Li S, Xu J, Makarenkova VP, et al: A novel epitope of N-CAM defines precursors of human adherent NK cells. J Leukoc Biol 76:1187-99, 2004

Vakkila J, DeMarco RA, Lotze MT: Imaging analysis of STAT1 and NF-kappaB translocation in dendritic cells at the single cell level. J Immunol Methods 294:123-34, 2004

Vakkila J, Lotze MT: Inflammation and necrosis promote tumour growth. Nat Rev Immunol 4:641-8, 2004

Vakkila J, Thomson AW, Vettenranta K, et al: Dendritic cell subsets in childhood and in children with cancer: relation to age and disease prognosis. Clin Exp Immunol 135:455-61, 2004

Vakkila J, Lotze MT, Riga C, et al: A basis for distinguishing cultured dendritic cells and macrophages in cytospins and fixed sections. Pediatr Dev Pathol 8:43-51, 2005

Vakkila J, Thomson AW, Hovi L, et al: Circulating dendritic cell subset levels after allogeneic stem cell transplantation in children correlate with time post transplant and severity of acute graft-versus-host disease. Bone Marrow Transplant 35:501-7, 2005

Vakkila J, Jaffe R, Michelow M, et al: Pediatric cancers are infiltrated predominantly by macrophages and contain a paucity of dendritic cells: a major nosologic difference with adult tumors. Clin Cancer Res 12:2049-54, 2006

Pettersson T, Partanen J, Vakkila J: Veritautien immunologiaa, in Ruutu T, Rajamäki A, Lassila R, et al (eds): Veritaudit (ed 3rd). Helsinki, Duodecim, 2007, pp 45-68

Vakkila J: Lasten terveyteen liittyviä huoleja ja akuutteja sairauksia, in Armanto A, Koistinen P (eds): Neuvolatyön käsikirja. Helsinki, Tammi, 2007, pp 173-179

Vakkila J: Lääkärin tekemä lapsen kasvun ja kehityksen seuranta neuvolassa, in Armanto A, Koistinen P (eds): Neuvolatyön käsikirja. Helsinki, Tammi, 2007

Vakkila J, Demarco RA, Lotze MT: Coordinate NF-kappaB and STAT1 activation promotes development of myeloid type 1 dendritic cells. Scand J Immunol 67:260-9, 2008

Vakkila J, Nieminen U, Siitonen S, et al: A novel modification of a flow cytometric assay of phosphorylated STAT1 in whole blood monocytes for immunomonitoring of patients on IFN alpha regimen. Scand J Immunol 67:95-102, 2008

Mansfield AS, Heikkila PS, Vaara AT, et al: Simultaneous Foxp3 and IDO expression is associated with sentinel lymph node metastases in breast cancer. BMC Cancer 9:231, 2009

Jalkanen SE, Vakkila J, Kreutzman A, et al: Poor cytokine-induced phosphorylation in chronic myeloid leukemia patients at diagnosis is effectively reversed by tyrosine kinase inhibitor therapy. Exp Hematol 39:102-113 e1, 2011

Kreutzman A, Rohon P, Faber E, et al: Chronic myeloid leukemia patients in prolonged remission following interferon-alpha monotherapy have distinct cytokine and oligoclonal lymphocyte profile. PLoS One 6:e23022, 2011

Mansfield AS, Heikkila P, von Smitten K, et al: Metastasis to sentinel lymph nodes in breast cancer is associated with maturation arrest of dendritic cells and poor co-localization of dendritic cells and CD8+ T cells. Virchows Arch 459:391-8, 2011

Savola S, Klami A, Myllykangas S, et al: High Expression of Complement Component 5 (C5) at Tumor Site Associates with Superior Survival in Ewing’s Sarcoma Family of Tumour Patients. ISRN Oncol 2011:168712, 2011

Mansfield AS, Heikkilä P, von Smitten K, et al: The presence of sinusoidal CD163+ macrophages in sentinel lymph nodes is associated with favorable nodal status in patients with breast cancer. Virchows Arch Dec;461(6):639-46. doi: 10.1007/s00428-012-1338-4. Epub 2012 Nov 13. PubMed PMID: 23149573, 2012

Nieminen JK, Vakkila J, Salo HM, et al: Altered phenotype of peripheral blood dendritic cells in pediatric type 1 diabetes. Diabetes Care 35:2303-10, 2012

Lankester AC, Berghuis D, Schilham MW, et al: The CXCR4-CXCL12 axis in Ewing sarcoma: promotion of tumor growth rather than metastatic disease. Clin Sarcoma Res. Dec 18;2(1):24. doi: 10.1186/2045-3329-2-24. 2012 PubMed PMID: 23249693; PubMed Central PMCID: PMC3549731.

Mustjoki S, Auvinen K, Kreutzman A, et al: Rapid mobilization of cytotoxic lymphocytes induced by dasatinib therapy in leukemia patients. Leukemia. Nov 29. doi: 10.1038/leu.2012.348. [Epub ahead of print] PubMed PMID: 23192016, 2012

Nieminen JK, Niemi M, Sipponen T, et al: Dendritic cells from Crohn’s disease patients show aberrant STAT1 and STAT3 signaling. PLoS One 8:e70738, 2013

Ilander M, Kreutzman A, Rohon P, et al: Enlarged memory T-cell pool and enhanced Th1-type responses in chronic myeloid leukemia patients who have successfully discontinued IFN-alpha monotherapy. PLoS One 9:e87794, 2014

Koskenvesa P, Kreutzman A, Rohon P, et al: Imatinib and pegylated IFN-alpha2b discontinuation in first-line chronic myeloid leukemia patients following a major molecular response. Eur J Haematol 92:413-20, 2014

Kreutzman A, Ilander M, Porkka K, et al: Dasatinib promotes Th1-type responses in granzyme B expressing T-cells. Oncoimmunology 3:e28925, 2014

Mustjoki S, Petterson T, Sinisalo M, Vakkila, J: Veritautien immunologiaa, in Remes K, Porkka K (eds): Veritaudit. Helsinki, Duodecim, 2015, pp 43-52

Vakkila J, Koskinen JO, Brandt A, et al: Detection of Group A Streptococcus from Pharyngeal Swab Samples by Bacterial Culture Is Challenged by a Novel mariPOC Point-of-Care Test. J Clin Microbiol 53:2079-83, 2015

Gunell M et al: Comprehensive real-time epidemiological data from respiratory infections in Finland between 2010 and 2014 obtained from an automated and multianalyte mariPOC® respiratory pathogen test. European Journal of Clinical Microbiology & Infectious Diseases. Eur J Clin Microbiol Infect Dis. 2016 Mar;35(3):405-13. doi: 10.1007/s10096-015-2553-0. Epub 2016 Jan 6